KORELASI ANTARA HASIL TES MIKROSKOPIS DENGAN TES CEPAT MOLEKULER PADA PASIEN TUBERCULOSIS DAN MULTIDRUG RESISTEN TUBERCULOSIS DI RSUD Dr. H CHASAN BOESOIRIE TERNATE
Sari
Tuberculosis (TB) is a pulmonary disease caused by Mycobacterium tuberculosis. Globally in 2018 the
estimated number of people affected by TB was estimated at 10.0 million population and 484,000 cases of
multidrug-resistant TB (MDR-TB). This study aims to determine the correlation between microscopic test
results with RMT on TB and MDR-TB patients at RSUD Dr. H Chasan Boesoirie Ternate. This type of research
is analytical research using a retrospective approach. The sample in this study were patients with suspected TB
and MDR-TB who had performed microscopic tests and TCM in February – April at 2020 in the Clinical
Pathology Laboratory of RSUD Dr. H Chasan Boesoirie Ternate, who met the inclusion and exclusion criteria.
Data were analyzed using the SPSS program analysis was carried out in stages, namely by univariate and
bivariate using chi-square test. From 100 samples, the results of RMT examination with TB suspects were 30
rifampicin sensitive samples with 2 rifampicin resistance and 5 rifampin sensitive samples for TB MDR-TB
suspects RMT examination results. Chi-square test results obtained the value of p = 000 (p <0.05). There is still
a significant difference between the microscopic test results with RMT in TB and MDR-TB suspect patients at
RSUD Dr. H Chasan Boesoirie Ternate.
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World Health Organization. Global Tuberculosis Report. Workplace Health and Safety. 2018.
Kementerian Kesehatan RI. Pusat Data dan Informasi. 2019.
Laporan Hasil Riset Kesehatan Dasar (Riskesdas) Indonesia. Badan Penelitian dan Pengembangan
Kesehatan Kementerian RI. 2018.
Dinas kesehatan kota Ternate. Profil Kesehatan kota Ternate. 2019.
Sumual RL, Wahongan GJP, Tuda JSB. Deteksi Mycobacterium tuberculosis pada Sampel Sputum
menggunakan Teknik Loop-Mediated Isothermal Amplification (LAMP-TB). Jurnal e-Biomedik. 2017.
Kementerian Kesehatan RI. Pemeriksaan tuberkulosis menggunakan alat GeneXpert. Petunjuk Teknis.
Jakarta. 2015.
Tim Program TB St. Carolus. Tuberkulosis Dapat Disembuhkan. Jakarta KPG (Kepustakaan Populer
Gramedia). 2017.
Farhat MR, Shapiro BJ, Kieser KJ, Sultana. Genomic analysis identifies targets of convergent positive
selection in drug-resistant Mycobacterium tuberculosis. Nat Genet. 2017.
Price SAP. Konsep klinis proses-proses penyakit Ed 6. 2012.
PDPI. Pedoman Penatalaksanaan TB (Konsensus TB). Perhimpun Dr Paru Indonesia. 2014.
Dotulong JFJ, Sapulete MR, Kandou GD. Hubungan Faktor Risiko Umur, Jenis Kelamin Dan Kepadatan
Hunian Dengan Kejadian Penyakit Tb Paru Di Desa Wori Kecamatan Wori. Jurnal Kedokteran Komunitas
Dan Trop. 2015.
Sejati A, Sofiana L. Faktor-Faktor Terjadinya Tuberkulosis. Univ Ahmad Dahlan. 2015.
Maqfirah H. Faktor risiko kejadian tb paru di wilayah kerja puskesmas liukang tupabbiring kabupaten
pangkep. Univ Islam Negeri Allaudin. 2017.
Riza LL. Hubungan Perilaku Merokok dengan Kejadian Gagal Konversi Pasien Tuberkulosis Paru di Balai
Kesehatan Paru Masyarakat ( BKPM ) Wilayah Semarang Abstrak. Univ Negeri Semarang. 2017.
Groenewald W, Baird MS, Verschoor JA, Minnikin DE, Croft AK. Differential spontaneous folding of
mycolic acids from Mycobacterium tuberculosis. Chem Phys Lipids. 2018.
Endah S. Perbedaan Hasil Pemeriksaan Mikroskopis Dan GeneXpert Pada Sputum Suspek TB Kambuh .
Universitas Muhammadiyah Semarang. 2018.
Nurlia Naim Nud. Performa Tes Cepat Molekuler Dalam Diagnosa Tuberkulosis Di Balai Besar Kesehatan
Paru Masyarakat. Makassar. 2018.
Amalia Z. Profil Hasil Pemeriksaan Mycobacterium Tuberculosis Menggunakan GeneXpert Pada Pasien
Di Rumah Sakit Umum Kota Tangerang Selatan Periode Juni 2016-Juni 2017. Kedokteran Univ Islam
Negeri Syarif Hidayatullah. Jakarta. 2017.
Azwar GA, Noviana DI, Hendriyono F. Karakteristik Penderita Tuberkulosis Paru Dengan Multidrug-
Resistant Tuberculosis (MDR-TB) Di RSUD Ulin. Banjarmasin. 2017.
Aulia. Korelasi Antara Hasil Pemeriksaan Sputum Bta Dengan Hasil Pemeriksaan GeneXpert Pada Pasien
Tb-Mdr Di RSUD Dr.H. Abdul Moeloek Provinsi Lampung Periode Tahun 2015-2016. Lampung. 2017.
Bisara D, dkk. Pemanfaatan Tes Cepat Molekuler (TCM) GeneXpert Sebagai Alat Diagnostik TB Paru di
RSUD Wangaya Kota Denpasar. Jurnal Ekologi Kesehatan. 2019.
Rivani E. Perbandingan uji diagnostik GeneXpert MTB/RIF untuk mendeteksi resistensi rifampicin
Mycobacterium tuberculosis pada pasien TB paru di RSUP dr. Moh.Hoesin Palembang. Universitas
Sriwijaya. 2019.
Vinuesa V. Performance of a Highly Sensitive Mycobacterium tuberculosis Complex Real-Time PCR
Assay for Diagnosis of Pulmonary Tuberculosis in a Low-Prevalence Setting: a Prospective Intervention
Study. Journal of Clinical Microbiology. 2018.
Sandjaja M , Lipoarabinomannan Urin Sebagai Alat Diagnostik Tuberkulosis Paru Pada Pasien Human
Immunodeficiency Virus. Universitas Udayana Denpasar. 2018.
Kemal, dkk. Comparison of a real-time polymerase chain reaction-based system and Erlich–Ziehl–Neelsen
method with culture in the identification of Mycobacterium tuberculosis. Turkish Journal of Medical
Sciences. 2016.
DOI: https://doi.org/10.33387/kmj.v2i1.2324
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