POLA JUMLAH TROMBOSIT PADA ANAK YANG MENDERITA DEMAM DENGUE (DF) DAN DEMAM BERDARAH DENGUE (DHF) DI RSUD Dr H CHASAN BOESOIRIE TERNATE PERIODE JANUARI-NOVEMBER 2019

Marhaeni Hasan

Sari


Dengue is an acute virus infectious disease caused by the dengue virus and transmitted by Aedes
aegypty mosquitoes with high mortality and morbidity in many regions of the world. Thrombocytopenia is one
of the laboratory parameters in diagnosing dengue virus infection that has the possibility to change day by day.
To study the thrombocyte count pattern in dengue fever (DF) and dengue haemorrhagic fever (DHF) in
pediatrics patient. This type of research is a cross sectional analytic study with a retrospective design, using
secondary data from medical records in Pediatrics department of Dr H Chasan Boesoirie distric hospital
during January-November 2019 period. The research sample was aged <15 years, diagnosis of DF and DHF
according to WHO 2011 criteria, the data regarding thrombocyte counts, days of sickness, the patient’s
characteristics and for statistical analysis Mann-whitney test was used. On average, the thrombocyte count in
DF patients starts dropping by the 4th day. It reaches its lowest point on the 5th day and starts going up on 6th
day. In DHF patients, on average, the thrombocyte count drops by the 3rd day, hits lowest point on the 5th, and
goes back up on the 6th day. In DHF patients with shock, the average thrombocyte count on the 3rdday is 50.000
cells/mm3 while the lowest count, on average on the 6th day is 42.000 cells/mm3. This number starts going up on
the 7th day. There is a significant difference in the average thrombocyte count between DF and DHF patients
on the 3rd, 4th, 5th, and 6th day (p<0.05) . As for DHF patients without shock, a significant difference was found
on the 6th day (51.000 cells/mm3 and 81.000 cells/mm3, p=0.047). There is a significant difference in the
average thrombocyte counts between DF and DHF patients. The declining count to <100,000 cells/mm3 on the
3rd day of sickness has to be taken cautiously in order to prevent from making the shock worse.


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DOI: https://doi.org/10.33387/kmj.v2i1.2325

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