Email the author 
Phytochemicals Screening and Antibacterial Activity of Teijsmaniadendron Holrungii from West Papua
Abstract
Papua is an island with the highest flora biodiversity in the world. To date, the phytochemical content and antibacterial bioactivity of the Teijsmaniadendron holrungii plant from West Papua have never been reported. In this study, phytochemical screening and bioactivity tests of T. holrungii bark ethanol extract against E. coli and S. aureus bacteria were carried out. The results showed that T. holrungii bark ethanol extract contained alkaloids, flavonoids, steroids, and tannins. The inhibitory activity of bacterial growth increased with an increase in concentrations (w/v) of 5; 10; 20; 40; and 80%, with inhibitory zones of 14.5; 17; 18; 20; and 22 mm for E. coli bacteria and 4.5; 5.5; 6; 7.5; and 9.5 mm for S. aureus bacteria.
Keywords
Full Text:
PDFReferences
Agidew, M. G. (2022). Phytochemical Analysis of Some Selected Traditional Medicinal Plants in Ethiopia. Bulletin of the National Research Centre, 46(1). https://doi.org/10.1186/s42269-022-00770-8.
Agusta, A., Wulansari, D., Praptiwi, Fathoni, A., Oktavia, L., & Keim, A. P. (2022). Papuacerdrus Papuana (f. Muell) h.l.li., A New Source for Two Bioactive Diterpenes: Ferruginol and Trans-Communic Acid That Virtually Active Against Sars-Cov-2. Rasayan Journal of Chemistry, 15(2), 1378–1385. https://doi.org/10.31788/RJC.2021.1526749
Alghazeer, R., Azwai, S., Garbaj, A. M., Amr, A., Elghmasi, S., Sidati, M., Yudiati, E., Kubbat, M. G., Eskandrani, A. A., Shamlan, G., & Alansari, W. S. (2022). Alkaloids Rich Extracts from Brown Algae Against Multidrug-Resistant Bacteria by Distinctive Mode of Action. Arabian Journal for Science and Engineering, 47(1), 179–188. https://doi.org/10.1007/s13369-021-05592-w
Baker, D. H. A. (2022). An Ethnopharmacological Review on The Therapeutical Properties of Flavonoids and Their Mechanisms of Actions : A Comprehensive Review Based On Up To Date Knowledge. Toxicology Reports, 9, 445–469. https://doi.org/10.1016/j.toxrep.2022.03.011
Cámara-Leret, R., Frodin, D. G., Adema, F., Anderson, C., Appelhans, M. S., Argent, G., Arias Guerrero, S., Ashton, P., Baker, W. J., Barfod, A. S., Barrington, D., Borosova, R., Bramley, G. L. C., Briggs, M., Buerki, S., Cahen, D., Callmander, M. W., Cheek, M., Chen, C. W., … van Welzen, P. C. (2020). New Guinea Has The World’s Richest Island Flora. Nature, 584(7822), 579–583. https://doi.org/10.1038/s41586-020-2549-5
Carvalho, R. S., Carollo, C. A., de Magalhães, J. C., Palumbo, J. M. C., Boaretto, A. G., Nunes e Sá, I. C., Ferraz, A. C., Lima, W. G., de Siqueira, J. M., & Ferreira, J. M. S. (2018). Antibacterial and Antifungal Activities of Phenolic Compound-Enriched Ethyl Acetate Fraction from Cochlospermum Regium (Mart. Et. Schr.) Pilger Roots: Mechanisms of Action and Synergism With Tannin and Gallic Acid. South African Journal of Botany, 114, 181–187. https://doi.org/10.1016/j.sajb.2017.11.010
De Kok, R. P. J., Rusea, G., & Latiff, A. (2009). The Genus Teijsmanniodendron Koord. (Lamiaceae). Kew Bulletin, 64(4), 587–625. https://doi.org/10.1007/s12225-009-9156-9
Dias, D. A., Urban, S., & Roessner, U. (2012). A Historical Overview of Natural Products in Drug Discovery. Metabolites, 2(2), 303–336. https://doi.org/10.3390/metabo2020303
Felisbino, J. K. R. P., Vieira, B. S., de Oliveira, A., da Silva, N. A., Martins, C. H. G., Santiago, M. B., Munoz, R. A. A., Cunha, L. C. S., & Sousa, R. M. F. (2021). Identification of Substances Produced by Cercospora Brachiata in Absence of Light and Evaluation of Antibacterial Activity. Journal of Fungi, 7(9), 1–10. https://doi.org/10.3390/jof7090680
Hara, F. L. K., Nunaki, J. H., & Sadsoeitoeboen, M. J. (2009). Pemanfaatan Tumbuhan Sebagai Obat Tradisional oleh Masyarakat Suku Maybrat di Kampung Renis Distrik Mare Kabupaten Sorong Selatan. Natural, 8(1), 29–36.
Harbone, J. B. (1998). Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis (Third Edit). London: Chapman & Hall.
Hasan, M. M., Roy, P., Alam, M., Hoque, M. M., & Zzaman, W. (2022). Antimicrobial Activity of Peels and Physicochemical Properties of Juice Prepared from Indigenous Citrus Fruits of Sylhet Region, Bangladesh. Heliyon, 8(7), 1–7. https://doi.org/10.1016/j.heliyon.2022.e09948
Herrera, K. M. S., Lopes, G. F. M., Oliveira, M. E., Sousa, J. F., Lima, W. G., Silva, F. K., Brito, J. C. M., Gomes, A. J. P. S., Viana, G. H. R., Soares, A. C., & Ferreira, J. M. S. (2022). A 3-alkylpyridine-bearing Alkaloid Exhibits Potent Antimicrobial Activity Against Methicillin-Resistant Staphylococcus Aureus ( MRSA ) with No Detectable Resistance Microbiological Research A 3-alkylpyridine-Bearing Alkaloid Exhibits Potent Antimicrobial. Microbiological Research, 261, 127073. https://doi.org/10.1016/j.micres.2022.127073
Maisetta, G., Batoni, G., Caboni, P., Esin, S., Rinaldi, A. C., & Zucca, P. (2019). Tannin Profile, Antioxidant Properties, and Antimicrobial Activity of Extracts from Two Mediterranean Species of Parasitic Plant Cytinus. BMC Complementary and Alternative Medicine, 19(1), 1–11. https://doi.org/10.1186/s12906-019-2487-7
Nadaraia, N. S., Amiranashvili, L. S., Merlani, M., Kakhabrishvili, M. L., Barbakadze, N. N., Geronikaki, A., Petrou, A., Poroikov, V., Ciric, A., Glamoclija, J., & Sokovic, M. (2019). Novel Antimicrobial Agents’ Discovery Among The Steroid Derivatives. Steroids, 144, 52–65. https://doi.org/10.1016/j.steroids.2019.02.012
Ndezo Bisso, B., Njikang Epie Nkwelle, R., Tchuenguem Tchuenteu, R., & Dzoyem, J. P. (2022). Phytochemical Screening, Antioxidant, and Antimicrobial Activities of Seven Underinvestigated Medicinal Plants against Microbial Pathogens. Advances in Pharmacological and Pharmaceutical Sciences, 2022. https://doi.org/10.1155/2022/1998808
Olchowik-Grabarek, E., Sękowski, S., Kwiatek, A., Płaczkiewicz, J., Abdulladjanova, N., Shlyonsky, V., Swiecicka, I., & Zamaraeva, M. (2022). The Structural Changes in the Membranes of Staphylococcus aureus Caused by Hydrolysable Tannins Witness Their Antibacterial Activity. Membranes, 12(11), 1124. https://doi.org/10.3390/membranes12111124
Parubak, A. . (2010). Uji Aktivitas Antibakteri dari Estrak Tumbuhan Akway (Drimys beccariana. Gibbs). Natural, 9(1), 8–12.
Rabizadeh, F., Mirian, M. S., Doosti, R., Kiani-Anbouhi, R., & Eftekhari, E. (2022). Phytochemical Classification of Medicinal Plants Used in the Treatment of Kidney Disease Based on Traditional Persian Medicine. Evidence-Based Complementary and Alternative Medicine, 2022. https://doi.org/10.1155/2022/8022599
Restianti, Santoso, B. B., & Pulung, M. L. (2020). Uji Aktivitas Antibakteri dan Skrining Fitokimia Ekstrak Heksana, Etil Asetat dan Metanol Tumbuhan Suruhan (Peperomia pellucida L. Kunth). Jurnal Natural, 16(2), 105–111. https://doi.org/10.30862/jn.v16i2.114
Sadsoeitoeboen, M. J., & Kilmaskossu, J. . (2010). Tumbuhan Berkhasiat Obat yang Dimanfaatkan Suku Moor di Pulau Ratewi, Kampung Arui, Distrik Napan - Weinami Kabupaten Nabire. Natural, 9(1), 1–3.
Shamsudin, N. F., Ahmed, Q. U., Mahmood, S., Adnan, S., Shah, A., Khatib, A., Mukhtar, S., Alsharif, M. A., Parveen, H., & Zakaria, Z. A. (2022). Antibacterial Effects of Flavonoids and Their Structure-Activity Relationship Study : A Comparative Interpretation. 27(1149), 1–43. https://doi.org/10.3390/molecules27041149
Sharaf, M. H., Abdelaziz, A. M., Kalaba, M. H., Radwan, A. A., & Hashem, A. H. (2022). Antimicrobial, Antioxidant, Cytotoxic Activities and Phytochemical Analysis of Fungal Endophytes Isolated from Ocimum Basilicum. Applied Biochemistry and Biotechnology, 194(3), 1271–1289. https://doi.org/10.1007/s12010-021-03702-w
Siahaan, E. M. I., Santoso, B. B., Somar, E., & Massora, M. (2021). Uji Aktivitas Antibakteri dan Skrining Fitokimia Ekstrak Metanol Buah Hitam ( H . monticola . ) Asal Kabupaten Teluk Wondama. Natural, 17(2), 72–84.
Sulaiman, M., Jannat, K., Nissapatorn, V., Rahmatullah, M., Paul, A. K., Pereira, M. D. L., Rajagopal, M., Suleiman, M., Butler, M. S., Khaled, M., Break, B., Wilairatana, P., & Wiart, C. (2022). Antibacterial and Antifungal Alkaloids from Asian Angiosperms : Clinical Potentials. Antibiotics, 11(i), 1–38. https://doi.org/https://doi.org/10.3390/antibiotics11091146
Wronska, N., Szlaur, M., Zawadzka, K., & Lisowska, K. (2022). The Synergistic Effect of Triterpenoids and Flavonoids — New Approaches for Treating Bacterial Infections ? Molecules, 27(847), 1–11. https://doi.org/10.3390/molecules27030847
DOI: https://doi.org/10.33387/tjp.v12i1.5467
Refbacks
- There are currently no refbacks.
Copyright (c) 2023 sabir sumarna
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
TECHNO: Jurnal Penelitian
Published by: LPPM Universitas Khairun
Addres : Jalan Yusuf Abdurrahman Kampus II Unkhair, Kelurahan Gambesi, 97722 Kecamatan Kota Ternate Selatan, Provinsi Maluku Utara, Email: techno@unkhair.ac.id | URL: http://ejournal.unkhair.ac.id/index.php/Techno
Techno Jurnal Penelitian is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.